By means of intratracheal injection, particles of metalloid silicium about five microns in size are introduced into the lungs of guinea pigs, and the secondary parenchymatous reactions are studied from 10 minutes to 105 days. In the dust cells, the silicium is progressively broken up into very small particles of less than 1 micron in size. The cells do not show degeneration or mummification as the ordinary silica cells (Mavrogordato) do.
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Policard, A. Réactions cytologiques à l'introduction pulmonaire expérimentale de particules de silicium métalloïdique. Experientia 4, 113–114 (1948). https://doi.org/10.1007/BF02164441