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Release of histamine by cotton dust extracts from human lung tissuein vitro

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Baumwollextrakt, bei 37° mit zerkleinertem menschlichem Lungengewebe inkubiert, setzt daraus Histamin in ähnlichen Mengen wie Compound 48/80 frei.

Die Ergebnisse stützen die Hypothese, dass die Symptome der Byssinosis bei Baumwollspinnerei-Arbeitern mindestens teilweise durch eine Histamin-freisetzende Substanz im Baumwollstaub verursacht werden.

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    The authors thank ProfessorA. G. Brom (Leiden) and DocentN. P. Berg (Gothenburg) for their help in making surgical specimens of lung tissue available, Dr.L. Muller (Enschede) for supplying samples of cotton dust, and MissM.-B. Johansson for valuable technical assistance. This work was supported in part by research grants to one of us (A.B.) from the ‘Organisation for Health Research T.N.O.’ (The Hague) and the ‘Foundation for the Advancement of Medical Scientific Research’ (Arnhem).

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Bouhuys, A., Lindell, S.-. Release of histamine by cotton dust extracts from human lung tissuein vitro . Experientia 17, 211–212 (1961).

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  • Dust
  • Histamin
  • Human Lung
  • Cotton Dust
  • Dust Extract