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Novobiocin as uncoupling agent

Résumé

Les auteurs démontrent que la novobiocine provoque un découplement de l'oxydation phosphorylante dans un homogénat de foic de rat déjà à une concentration 1,575·10−4 M. Les rapports entre l'activité antibactérienne et l'action biochimique de l'antibiotique sont discutés.

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Frei, J., Canal, N. & Gori, E. Novobiocin as uncoupling agent. Experientia 14, 377–378 (1958). https://doi.org/10.1007/BF02159165

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Keywords

  • Novobiocin
  • Uncouple Agent