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Die lokale Leukozytenreaktion bei der intraperitonealen Infektion der Maus mitE. coli

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Intraperitoneal aggregation of leucocytes is produced in an identical manner by intraperitoneal application of different amounts of living and dead bacteria and bacterial products. The maximum accumulation occurs with medium dosages of bacteria or their products, with high dosages no leucocytic accumulation is produced. Pretreatment with selected LPS of bacteria enhances the intraperitoneal accumulation of leucocytes also with the high amounts of bacteria, whereas the reaction in not pretreated with LPS is suppressed. Parallel to the increase of the intraperitoneal leucocytic accumulation the animals are protected against the infection with high amounts of bacteria, to which they succumb if not pretreated with LPS.

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Ecklin, B., Meier, R. Die lokale Leukozytenreaktion bei der intraperitonealen Infektion der Maus mitE. coli . Experientia 16, 112–113 (1960). https://doi.org/10.1007/BF02158093

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