Experientia

, Volume 10, Issue 6, pp 261–262

Zentralerregende Wirkung eines neuen Piperidinderivates

  • J. Tripod
  • E. Sury
  • K. Hoffmann
Kurze Mitteilungen

DOI: 10.1007/BF02157398

Cite this article as:
Tripod, J., Sury, E. & Hoffmann, K. Experientia (1954) 10: 261. doi:10.1007/BF02157398

Summary

A new piperidine derivative, the 2-diphenylmethylpiperidine, produces already in doses of 0.001 g/kg s.c. a strong increase of the spontaneous motility of various animals. On mice it has about the same potency as d-desoxy-ephedrine and is about 3 times more potent than amphetamin. It also acts markedly antagonistic on various narcotics but has practically no peripheral sympathomimetic effects.

Copyright information

© Birkhäuser Verlag 1954

Authors and Affiliations

  • J. Tripod
    • 1
  • E. Sury
    • 1
  • K. Hoffmann
    • 1
  1. 1.Wissenschaftliche Laboratorien der CIBA AktiengesellschaftBasel

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