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Effects of thalidomide in the rat foetus

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Zusammenfassung

Thalidomidverabreichung an sch wangere Ratten führte zu keinen schweren Skelettmissbildungen bei den Neugeburten. Lediglich der fünfte Brustbeinkern blieb in der Entwicklung stark zurück und zeigte, besonders bei Tieren, welche Thalidomid in hohen Dosen erhielten, bizarre Formen. Die Zahl der Frucht-resorptionen war bei diesen Tieren erhöht.

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References

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Authors and Affiliations

  1. Laboratory of Physiological Chemistry, University of Amsterdam and the Netherlands Institute of Nutrition, Wageningen, The Netherlands

    H. J. Klein Obbink & L. M. Dalderup

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  1. H. J. Klein Obbink
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  2. L. M. Dalderup
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Klein Obbink, H.J., Dalderup, L.M. Effects of thalidomide in the rat foetus. Experientia 19, 645–646 (1963). https://doi.org/10.1007/BF02151297

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  • DOI: https://doi.org/10.1007/BF02151297

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