Experientia

, Volume 19, Issue 9, pp 467–469 | Cite as

The structure of theAspidosperma alkaloid compactinervine

  • C. Djerassi
  • Y. Nakagawa
  • J. M. Wilson
  • H. Budzikiewicz
  • B. Gilbert
  • L. D. Antonaccio
Kurze Mitteilungen

Keywords

Alkaloid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Es wird über die Isolierung eines neuen Alkaloids — Compactinervin — aus der brasilianischen Apocynaceen-ArtAspidosperma compactinervium Kuhlm. berichtet. Durch massenspektroskopische und Kernresonanz-Messungen und chemische Umwandlungen konnte gezeigt werden, dass es sich beim Compactinervin um 19,20-Dihydroxy-19,20-dihydro-akuammicin handelt. Seine vollständige Stereochemie sowie die des verwandten Alkaloids Lochneridin konnte abgeleitet werden. Compactinervin stellt die erste Verbindung vom Akuammicin-Typ dar, die aus einerAspidosperma-Art isoliert worden ist.

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References

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    No molecular ion peak could be obtained by means of the usual heated inlet system for compactinervine or any derivatives containing the two free hydroxyl groups, but satisfactory spectra were realized by means of the recently described direct inlet system (J. F. Lynch, J. M. Wilson, H. Budzikiewicz, andC. Djerassi, Experientia19, 211 (1963)).Google Scholar
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Copyright information

© Birkhäuser Verlag 1963

Authors and Affiliations

  • C. Djerassi
    • 1
    • 2
  • Y. Nakagawa
    • 1
    • 2
  • J. M. Wilson
    • 1
    • 2
  • H. Budzikiewicz
    • 1
    • 2
  • B. Gilbert
    • 1
    • 2
  • L. D. Antonaccio
    • 1
    • 2
  1. 1.Department of ChemistryStanford UniversityStanfordU.S.A.
  2. 2.Instituto de Quimica AgricolaRio de JaneiroBrazil

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