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Neurophysiology

, Volume 20, Issue 6, pp 542–548 | Cite as

Effect of stimulating periaqueductal gray matter on low- and high-threshold response of pontine and bulbar reticular neurons

  • M. V. Karpukhina
  • A. P. Gokin
  • Yu P. Limanskii
Article
  • 21 Downloads

Abstract

Electrical stimulation of the periaqueductal gray matter (PGM) bringing about inhibition of high-threshold mouth-opening reflex on somatosensory response of neurons belonging to the pontine caudal reticular nucleus (CN) and the reticular gigantocellular nucleus (GN) were investigated in cats under light chloralose-induced anesthesia. It was found that inhibitory effects on CN and GN neurons adhered to the principle of control over their main synaptic input: in GN neurons and particularly in “high-threshold” cells, inhibition mainly affected response to nociceptive stimuli, in contrast to CN neurons, and “low-threshold” cells in particular, where response to non-nociceptive stimulation was inhibited. The possible mechanisms and functional significance of the effects described are discussed.

Keywords

Gray Matter Electrical Stimulation Functional Significance Synaptic Input Reticular Nucleus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • M. V. Karpukhina
  • A. P. Gokin
  • Yu P. Limanskii

There are no affiliations available

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