Advertisement

Experientia

, Volume 4, Issue 11, pp 434–436 | Cite as

La teneur du noyau cellulaire en acide désoxyribonucléique à travers les organes, les individus et les espèces animales

  • R. Vendrely
  • C. Vendrely
Kurze Mitteilungen

Summary

Techniques are described for the isolation of nuclei from animals cells and for the determination of the desoxyribonucleic acid content for each nucleus. These techniques have already been used in order to study a few mammalian species. From the first results (especially in calf, ox and bull), it seems to appear that the nucleus of the somatic cells contains constantly the same amount of desoxyribonucleic acid, whatever tissue and animal we studied within the same species; and this amount is just the double of that of the haploid cells (spermatozoa) in the same animal. This result constitutes a strong argument, from the analytical point of view, for the theory according to which the desoxyribonucleic acid is considered to be the substrate of the hereditary characters of the species.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. 1.
    Voir spécialement l'article récent deJ. N. Davidson (Cold Spring Harbor Symp. Quant. Biol.12, 50 [1947]) qui résume les résultats de ses devanciers et donne la bibliographie de la question.Google Scholar
  2. 2.
    Voir notre note préliminaire:A. Boivin, R. Vendrely etC. Vendrely C. R. Acad. Sci.226, 1061 (1948).Google Scholar
  3. 3.
    G. Crossmon, Science85, 250 (1937).Google Scholar
  4. 3a.
    C. A. Stoneburg, J. Biol. Chem.129, 189 (1939).Google Scholar
  5. 3b.
    A. Marshak, J. Gen. Physiol.25, 275 (1941).CrossRefGoogle Scholar
  6. 3c.
    M. Laskowski, Proc. Soc. Exp. Biol. Med.49, 354 (1942).Google Scholar
  7. 3d.
    A. Lazarow, J. Biol. Chem.140, 75 (1941).Google Scholar
  8. 3e.
    A. Dounce, J. Biol. Chem.147, 685 (1943) et151, 235 (1943).Google Scholar
  9. 1.
    W. C. Schneider, J. Biol. Chem.161, 293 (1945).Google Scholar
  10. 2.
    R. Vendrely etR. Sarciron, Bull. Soc. Chim. biol.26, 214 (1944).Google Scholar
  11. 3.
    Z. Dische, Mikrochemie8, 4 (1930).Google Scholar
  12. 4.
    H. v. Euler etL. Hahn, Svenks kem. Tidskr.58, 251 (1946).Google Scholar
  13. 5.
    G. Schmidt etS. J. Thannhauser, J. Biol. Chem.161, 83 (1945).Google Scholar
  14. 1.
    A. E. Mirsky etA. W. Pollister, Biol. Symp.10, 247 (1943).Google Scholar
  15. 1a.
    A. E. Mirsky, Adv. Enzymol.3, 1 (1943).Google Scholar
  16. 1b.
    A. W. Pollister etA. E. Mirsky, J. Gen. Physiol.30, 101 (1946).CrossRefGoogle Scholar
  17. 1c.
    A. E. Mirsky etA. W. Pollister, J. Gen. Physiol.30, 117 (1946).CrossRefGoogle Scholar
  18. 2.
    Ch. A. Zittle etB. Zitin, J. Biol. Chem.144, 99 (1942).Google Scholar
  19. 1.
    A. Boivin, A. Delaunay, R. Vendrely etY. Lehoult, Exper.1, 334 (1945);2, 139 (1946); CR. Acad. Sci.221, 718 (1945).Google Scholar
  20. 1a.
    A. Boivin, R. Vendrely etY. Lehoult, CR. Acad. Sci.221, 646 (1945).Google Scholar
  21. 1b.
    A. Boivin etR. Vendrely, Exper.3, 32 (1947).CrossRefGoogle Scholar
  22. 1c.
    A. Boivin, Cold Spring Harbor Symp. Quant. Biol.12, 7 (1947).Google Scholar
  23. 1.
    Voir par exemple:A. Boivin, R. Tulasne etR. Vendrely, CR. Acad. Sci.225, 703 (1947).Google Scholar
  24. 1a.
    A. Boivin, R. Vendrely etR. Tulasne, Arch. Sci. Physiol.1, 35 (1947).Google Scholar
  25. 1b.
    A. Boivin, R. Tulasne, R. Vendrely etR. Minck, Arch. Sci. Physiol.1, 307 (1947).Google Scholar

Copyright information

© Birkhäuser Verlag 1948

Authors and Affiliations

  • R. Vendrely
    • 1
  • C. Vendrely
    • 1
  1. 1.Laboratoire de biologie bactérienne du Centre national de la recherche scientifique et Institut de bactériologie de la Faculté de médecine de StrasbourgFrance

Personalised recommendations