Experientia

, Volume 20, Issue 11, pp 650–651 | Cite as

Ein Beitrag über die Art der Wirkung einiger Antituberkulotika

  • Z. Pelikan
  • B. Mičánek
  • P. Rohan
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Summary

The direct effect of any antituberculotics on pancreatic lipase was studied by the modified method ofWillstätter. The antituberculotics were found to activate the pancreatic lipase in the presence of Ca++. Any cations, especially copper, decreases the lipase activity. Increasing antituberculotics concentration is accompanied by an increasing effect on the lipolytic action of lipase.

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Literatur

  1. 1.
    R. Willstätter, E. Waldschmidt-Leitz undF. Memmen, Z. physiol. Chem.125, 93 (1923).Google Scholar
  2. 2.
    R. Willstätter undE. Waldschmidt-Leitz, Z. physiol. Chem.125, 132 (1923).Google Scholar
  3. 3.
    P. Desnuelle, M. Naudet undM. J. Constantin, Biochim. biophys. Acta5, 561 (1950).CrossRefPubMedGoogle Scholar
  4. 4.
    J. B. Sumner undG. F. Somers,Chemistry and Methods of Enzymes (Academic Press Inc., New York 1953), p. 80.Google Scholar

Copyright information

© Birkhäuser Verlag 1964

Authors and Affiliations

  • Z. Pelikan
    • 1
  • B. Mičánek
    • 1
  • P. Rohan
    • 1
  1. 1.Abteilung AllergologieDermatovenerologische Klinik der Universität J. E. P.BrnoTschechoslowakei

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