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Histopathological findings in eyes after silicone oil injection

  • B. Kirchhof
  • U. Tavakolian
  • H. Paulmann
  • K. Heimann
Article

Abstract

Eight eyes were examined histologically after silicone oil injection. Intraretinal deposits suggestive of silicone were not present in attached retinas, but were frequently observed in detached retinas when subretinal silicone occurred. This may possibly be due to defects in the horizontal conducting structures of the retina such as those occurring in persistent detachment with disorganization of the retina. Morphologically, the retina was essentially normal 3.5 years after the silicone injection. This observation contradicts the idea that silicone oil has a toxic effect.

Keywords

Public Health Silicone Retina Toxic Effect Histopathological Finding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Kirchhof B, Heimann K (1982) Lichtmikroskopische Befunde nach intraokularer Silikonölinjektion beim Menschen, Sitzungsberichte der 142. Versammlung des Vereins Rheinisch-Westfalischer Augenärzte, pp 195–199Google Scholar
  2. Laroche L, Pavlakis C, Saraux H, Orcel L (1983) Ocular findings following intravitreal silicone injection. Arch Ophthalmol 101: 1422–1425PubMedGoogle Scholar
  3. Leaver PK, Grey RHB, Garner A (1979) Silicone oil injection in the treatment of massive preretinal retraction. II. Late complications in 93 eyes. Br J Ophthalmol 63: 361–367PubMedGoogle Scholar
  4. Mukai N (1971) Silicone oil and nerve tissue damage — pathogenesis of silicone retinopathy as an example. Brain Nerve (Tokyo) 23: 793–803Google Scholar
  5. Mukai N, Lee PF, Schepens CL (1972) Intravitreous injection of silicone: an experimental study. II. Histochemistry and electron microscopy. Ann Ophthalmol 4: 273–287PubMedGoogle Scholar
  6. Mukai N, Lee PF, Oguri M, Schepens CL (1975) A long-term evaluation of silicone retinopathy in monkeys. Can J Ophthalmol 10: 391–402PubMedGoogle Scholar
  7. Ni C, Wang WJ, Albert DM, Schepens CL (1983) Intravitreous silicone injection. Arch Ophthalmol 101: 1399–1401PubMedGoogle Scholar
  8. Rentsch FJ, Atzler P, Liesenhoff H (1978) Histologische und elektronenmikroskopische Untersuchungen an einem menschlichen Auge nach mehrjähriger intravitrealer Silikonimplantation. Ber Zusammenkunft Dtsch Ophthalmol Ges 75: 70–74PubMedGoogle Scholar
  9. Stefani FH (1983) Gewebsreakationen auf nieder- und hochvisköses Silikonöl. Meeting of the Bayr Ophthalmol Ges, München, 31 October to 1 NovemberGoogle Scholar
  10. Sugar HS, Okamura ID (1976) Intravitreal silicone injection. Arch Ophthalmol 94: 612–615PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • B. Kirchhof
    • 1
  • U. Tavakolian
    • 1
  • H. Paulmann
    • 1
  • K. Heimann
    • 1
  1. 1.Department of Ophthalmology, Vitreoretinal SurgeryUniversity of CologneCologneFederal Republic of Germany

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