, Volume 43, Issue 5, pp 574–576 | Cite as

Dose relationships of morning bright white light in seasonal affective disorders (SAD)

  • A. Wirz-Justice
  • A. C. Schmid
  • P. Graw
  • K. Kräuchi
  • P. Kielholz
  • W. Pöldinger
  • H. -U. Fisch
  • C. Buddeberg
Short Communications


Bright white full spectrum light (>2500 lux) can improve depressive symptomatology in a selected group of patients with recurrent autumn and winter depression. This crossover study demonstrates that 0.5-h morning white light is not an effective treatment, whereas 2-h is.

Key words

Bright white light seasonal affective disorder dose relationships 


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  1. 1.
    Lewy, A.J., Wehr, T.A., Goodwin, F.K., Newsome, D.A., and Markey, S.P., Science210 (1980) 1267.PubMedGoogle Scholar
  2. 2.
    Lingjaerde, O., Bratlid, T., and Hansen, T., Acta psychiatr. scand.71 (1985) 506.PubMedGoogle Scholar
  3. 3.
    Czeisler, C.A., Allan, J.S., Strogatz, S.H., Ronda, J.M., Sanchez, R., Rios, C.D., Freitag, W.O., Richardson, G.S., and Kronauer, R.E., Science233 (1986) 667.PubMedGoogle Scholar
  4. 4.
    Daan, S., and Lewy, A.J., Psychopharmac. Bull.20 (1984) 566.Google Scholar
  5. 5.
    Rosenthal, N.E., Sack, D.A., Gillin, J.C., Lewy, A.J., Goodwin, F.K., Davenport, Y., Mueller, P.S., Newsome, D.A., and Wehr, T.A., Archs gen. Psychiat.41 (1984) 72.Google Scholar
  6. 6.
    Rosenthal, N.E., Sack, D.A., James, S.P., Parry, B.L., Mendelson, W.B., Tamarkin, L., and Wehr, T.A., Ann. N.Y. Acad. Sci.453 (1985) 260.PubMedGoogle Scholar
  7. 7.
    Gwinner, E., in: Handbook of Behavioural Neurobiology, vol. 4, p. 382. Ed. J. Aschoff. Plenum Press, New York 1981.Google Scholar
  8. 8.
    Aschoff, J., in: Handbook of Behavioural Neurobiology, vol. 4, p. 475. Ed. J. Aschoff. Plenum Press, New York 1981.Google Scholar
  9. 9.
    Rosenthal, N.E., Sack, D.A., and Wehr, T.A., in: Circadian Rhythms in Psychiatry, p. 185. Eds T.A. Wehr and F.K. Goodwin. Boxwood Press, Pacific Grove, California 1983.Google Scholar
  10. 10.
    Wirz-Justice, A., and Richter, R., Psychiat. Res.1 (1979) 53.Google Scholar
  11. 11.
    Lewy, A.J., Kern, H.E., Rosenthal, N.E., and Wehr, T.A., Am. J. Psychiat.139 (1982) 1496.PubMedGoogle Scholar
  12. 12.
    Quitkin, F., Terman, M., Terman, J., McGrath, P., and Stewart, J., ACNP Meeting 1986, abstracts p. 52.Google Scholar
  13. 13.
    Thompson, C., Isaacs, G., and Miles, A., Symposium ‘Latest findings on the aetiology and therapy of depression’. Basel 1986, abstracts p. 136b.Google Scholar
  14. 14.
    Checkley, S., Winton, F., Franey, C., and Korn, T., Lecture at the Royal College of Psychiatry, Southampton, England, June 1986.Google Scholar
  15. 15.
    Wehr, T.A., Jacobsen, F.M., Sack, D.A., Arendt, J., Tamarkin, L., and Rosenthal, N.E., Archs gen. Psychiat.43 (1986) 870.Google Scholar
  16. 16.
    Wirz-Justice, A., Bucheli, C., Graw, P., Kielholz, P., Fisch, H.-U., and Woggon, B., Acta psychiatr. scand.74 (1986) 193.PubMedGoogle Scholar
  17. 17.
    Lewy, A.J., Sack, R.L., and Singer, C.M., Psychopharmac. Bull.21 (1985) 368.Google Scholar
  18. 18.
    Terman, M., Terman, J.S., Quitkin, F.M., McGrath, P.J., and Stewart, J.W. (1987) manuscript submitted.Google Scholar
  19. 19.
    Wirz-Justice, A., Bucheli, C., Schmid, A.C., and Graw, P., Am. J. Psychiat.143 (1986) 932.Google Scholar
  20. 20.
    Hellekson, C.J., Kline, J.A., and Rosenthal, N.E., Am. J. Psychiat.143 (1986) 1035.PubMedGoogle Scholar
  21. 21.
    Yerevanian, B.I., Anderson, J.L., Grota, L.J., and Bray, M., Psychiat. Res.18 (1985) 355.Google Scholar
  22. 22.
    Lewy, A.J., and Sack, R.L., Proc. Soc. exp. Biol. Med.183 (1986) 11.PubMedGoogle Scholar
  23. 23.
    James, S.P., Parry, B.L., Carpenter, C.J., Kline, J., Sack, D.A., Wehr, T.A., and Rosenthal, N.E., Br. J. Psychiat.147 (1985) 260.Google Scholar
  24. 24.
    Lewy, A.J., Sack, R.L., Miller, L.S., and Hoban, T.M., Science235 (1987) 352.PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag Basel 1987

Authors and Affiliations

  • A. Wirz-Justice
    • 1
  • A. C. Schmid
    • 1
  • P. Graw
    • 1
  • K. Kräuchi
    • 1
  • P. Kielholz
    • 1
  • W. Pöldinger
    • 1
  • H. -U. Fisch
    • 2
  • C. Buddeberg
    • 3
  1. 1.Psychiatric University ClinicBaselSwitzerland
  2. 2.Psychiatric University PoliclinicBernSwitzerland
  3. 3.Psychiatric University PoliclinicZürichSwitzerland

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