Testicular histology in Klinefelter's syndrome
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Abstract
In 36 patients the diagnosis of Klinefelter's syndrome could not be made from the somatic status. A germinative sex examination must usually be carried out. Some set rules which are not applicable to all cases are outlined. Bearing this in mind, 3 groups are set up (excessive Leydig cell hyperplasia without tubuli, excessive Leydig cell hyperplasia with tubuli, incomplete or complete spermiogenesis) which will enable a better study. The relevant findings are tabulated and discussed. It shows that in Klinefelter's syndrome a great variability of testicular histology is to be expected. Special attention is devoted to 2 cases of histologically confirmed testicular spermatogenesis and aspermia in the ejaculate. It is suggested that a chromosomal disorder goes hand in hand with testicular histological findings, whereby all variations are possible.
Keywords
Public Health Histological Finding Great Variability Leydig Cell Cell HyperplasiaPreview
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