, Volume 48, Issue 8, pp 729–731

Presence of a partial urea cycle in the leech,Poecilobdella granulosa

  • S. Natesan
  • B. Jayasundaramma
  • R. Ramamurthi
  • S. R. R. Reddy
Research Articles


Ornithine carbamoyltransferase (OCT) and arginase, but not arginine synthetase (AS), were detected in the body wall and gut tissues of the leech. The activities of these enzymes were not altered by starvation. The high activity of arginase in body wall is probably due to the association of the latter with botryoidal tissue. Hirudineans, which evolved from oligochaete ancestors, appear to have lost the citrulline-arginine segment of the urea cycle due to their ammonotelic mode of nitrogen excretion.

Key words

Urea cycle leech botryoidal tissue hirudineans evolution 


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  1. 4.
    Florkin, M., in: Chemical Zoology, vol. 4, p. 147. Eds M. Florkin and B. T. Scheer. Academic Press, New York 1969.Google Scholar
  2. 5.
    Needham, A. E., in: Comparative Biochemistry of Nitrogen Metabolism, vol. 1, p. 207. Ed. J. W. Campbell. Academic Press, New York 1970.Google Scholar
  3. 6.
    Robin, Y., Audit, C., and Thoai, N. V., C. r. Se. Soc. Biol.156 (1962) 1232.Google Scholar
  4. 7.
    Bishop, S. H., and Campbell, J. W., Comp. Biochem. Physiol.15 (1965) 51.CrossRefPubMedGoogle Scholar
  5. 8.
    Prento, P., Comp. Biochem. Physiol.93B (1989) 509.CrossRefGoogle Scholar
  6. 9.
    Ramamurthi, R., Comp. Biochem. Physiol.24 (1968) 283.CrossRefPubMedGoogle Scholar
  7. 10.
    Baby, T. G., and Reddy, S. R. R., J. comp. Physiol.140B (1980) 261.Google Scholar
  8. 11.
    Arjunwadkar, A. V., and Reddy, S. R. R., Physiol. Zool.62 (1989) 1031.Google Scholar
  9. 12.
    Campbell, J. W., in: Comparative Animal Physiology, p. 279. Ed. C. L. Prosser. W. B. Saunders Co., Philadelphia 1973.Google Scholar
  10. 13.
    Thoai, N. V., and Robin, Y., in: Chemical Zoology, vol. 4, p. 163. Eds M. Florkin and B. T. Scheer. Academic Press, New York 1969.Google Scholar
  11. 14.
    Needham, A. E., Comp. Biochem. Physiol.5 (1967) 69.Google Scholar
  12. 15.
    Bradbury, S., Qu. J. microsc. Sci.100 (1957) 483.Google Scholar
  13. 16.
    Mann, K. H., Leeches (Hirudinea): Their Structure, Physiology, Ecology and Embryology. Pergamon Press, New York 1962.Google Scholar
  14. 17.
    Robin, Y., Audit, C., and Landon, M., Comp. Biochem. Physiol.22 (1967) 789.Google Scholar
  15. 18.
    Huggins, A. K., and Munday, K. A., in: Advances in Comparative Physiology and Biochemistry, vol. 3, p. 271. Ed. O. Lowenstein. Academic Press, New York 1968.Google Scholar
  16. 19.
    Wilson, R. P., Comp. Biochem. Physiol.46b (1973) 625.CrossRefGoogle Scholar
  17. 20.
    Paulus, H., in: Current Topics in Cellular Regulation, vol. 22, p. 177. Eds B. L. Horecker and E. R. Stadtman. Academic Press, New York 1983.Google Scholar
  18. 21.
    Takiguchi, M., Matsubasa, T., Amaya, Y., and Mori, M., Bioassays10 (1989) 163.CrossRefGoogle Scholar
  19. 22.
    Russell-Hunter, W. D., A Life of Invertebrates. Macmillan Publishing Co., New York 1979.23 Cohen, P. P., in: The Urea Cycle, p. 21. Eds S. Grisolia, R. Baguena and F. Mayor, John Wiley, New York 1976.Google Scholar
  20. 24.
    Clarke, R. B., in: Chemical Zoology, vol. 4, p. 1. Eds M. Florkin and B. T. Scheer. Academic Press, New York 1969.Google Scholar

Copyright information

© Birkhäuser Verlag 1992

Authors and Affiliations

  • S. Natesan
    • 1
  • B. Jayasundaramma
    • 2
  • R. Ramamurthi
    • 2
  • S. R. R. Reddy
    • 1
  1. 1.Department of ZoologyUniversity of PoonaPuneIndia
  2. 2.Department of ZoologySri Venkateswara UniversityTirupatiIndia
  3. 3.Department of MedicineUMDNJ-New Jersey Medical SchoolNewarkUSA

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