Acute Epstein-Barr virus infections in children
Epstein-Barr virus (EBV)-IgM antibodies could be detected in the sera of 36 children, most of whom had symptoms of Infectious Mononucleosis (IM). The detection of these antibodies indicates recent EBV infection. Heterophile antibodies could not be demonstrated in 17 of the 36 children. In young children, < 3 years, no heterophile antibodies could be detected at all. In two babies with EBV-IgM-antibodies bronchopneumonia and in a third baby a severe hepatosplenomegaly was diagnosed. In the serum of an 11-year-old boy with a Burkitt Lymphoma, EBV-IgM antibodies were present.
Unable to display preview. Download preview PDF.
- 2.Bernstein, A.: Infectious mononucleosis. Medicine (Baltimore)19, 85–92 (1940).Google Scholar
- 3.Burrett, A. M.: The serological diagnosis of glandular fever (infectious mononucleosis): a new technique. J. Hyg. (Cambr.)41, 330–341 (1941).Google Scholar
- 4.Davidsohn, I., Lee, C. L.: Serological diagnosis of infectious monomucleosis. A comparative study of five tests. Amer. J. clin. Path.41, 115–126 (1964).Google Scholar
- 8.Henle, G., Henle, W., Diehl, V.: Relation of Burkitt's tumorassociated herpes-type virus to infectious mononucleosis. Proc. nat. Acad. Sci. (Wash.)59, 91–101 (1968).Google Scholar
- 9.Pfeiffer, E.: Drüsenfieber. Jb. Kinderheilk. phys. Erzieh.29, 257–263 (1889).Google Scholar