Neurological outcome after a severe herpes simplex encephalitis treated with acyclovir and β-interferon time course of intracranial pressure
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A severe herpes simplex encephalitis with documented intra-cerebral lesions and brain edema was treated successfully with acyclovir andβ-interferon. The increase in intracranial pressure during the second week was well controlled by ICP monitoring. Life-threatening pressure peaks were avoided through the use of thiopental, osmodiuretics, TRIS, and lidocaine.
Key wordsHerpes-Simplex encephalitis Intracranial pressure monitoring
Herpes simplex encephalitis
Cerebral perfusion pressure
mean arterial pressure
Cerebral computer tomography
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