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Capnocytophaga canimorsus septicemia: Fifth report of a cat-associated infection and five other cases

  • M. Valtonen
  • A. Lauhio
  • P. Carlson
  • J. Multanen
  • A. Sivonen
  • M. Vaara
  • J. Lähdevirta
Notes

Abstract

Capnocytophaga canimorsus is a fastidious, slow-growing, gram-negative, rod-shaped bacterium that belongs to the normal oral flora of dogs and cats. Human septicemic infections are associated with a high mortality; most cases occur in immunocompromised patients with a history of dog bite. The fifth case of cat-associated septicemia caused byCapnocytophaga canimorsus is described. The six case reports presented here point out the characteristics reported previously: (a) cats are a source of human infection; (b) alcohol abuse is an important risk factor for the development of septicemicCapnocytophaga canimorsus infection; (c) septicemic infection often manifests with disseminated intravascular consumption coagulopathy or purpura; and (d) some cases of septicemia in humans result from pets that lick skin ulcers.

Keywords

Alcohol Internal Medicine High Mortality Alcohol Abuse Purpura 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Bobo RA, Newton EJ: A previously undescribed gram-negative bacillus causing septicemia and meningitis. American Journal of Clinical Pathology 1976, 65: 564–569.PubMedGoogle Scholar
  2. 2.
    Westwell AJ, Kerr K, Spencer MB, Hutchinson DN: DF-2 infection. British Medical Journal 1989, 298: 116–117.Google Scholar
  3. 3.
    Hicklin H, Verghese A, Alvarez S: Dysgonic fermenter 2 septicemia. Reviews of Infectious Diseases 1987, 9: 884–889.PubMedGoogle Scholar
  4. 4.
    Zumla A, Lipscomb G, Corbett M, McCarthy M: Dysgonic fermenter-type 2: an emerging zoonosis. Report of two cases and review. Quarterly Journal of Medicine 1988, 68: 741–752.PubMedGoogle Scholar
  5. 5.
    Krol-van Straaten MJ, Landheer JE, de Maat CEM:Capnocytophaga canimorsus (formerly DF-2) infections: review of the literature. Netherlands Journal of Medicine 1990, 36: 304–309.PubMedGoogle Scholar
  6. 6.
    Kullberg B-J, Westendorp RGJ, Wout JWV, Meinders AE: Purpura fulminans and symmetrical peripheral gangrene caused byCapnocytophaga canimorsus (formerly DF-2) septicemia — a complication of dog bite. Medicine 1991, 70: 287–292.PubMedGoogle Scholar
  7. 7.
    Weber DJ, Hanssen AR: Infections resulting from animal bites. Infectious Disease Clinics of North America 1991, 5: 663–680.PubMedGoogle Scholar
  8. 8.
    Goldstein EJC: Bite wounds and infection. Clinical Infectious Diseases 1992, 14: 633–640.PubMedGoogle Scholar
  9. 9.
    Leonard F, Lima J, Gigi J, Wauters G: Un cas de septicemie à bacille grom negatif du groupe DF-2, suite à une morsure de chien. Acta Clinica Belgica 1987, 42: 173–176.PubMedGoogle Scholar
  10. 10.
    August JR: Dysgonic fermenter-2 infections. Journal of the American Veterinary Association 1988, 193: 1506–1508.Google Scholar
  11. 11.
    Howell JM, Woodward GR: Precipitous hypotension in the emergency department caused byCapnocytophaga canimorsus sp. nov. sepsis. American Journal of Emergency Medicine 1990, 8: 312–314.PubMedGoogle Scholar
  12. 12.
    Hantson P, Gautier PE, Vekemans M-C, Fievez P, Evrard P, Wauters G, Mahieu P: FatalCapnocytophaga canimorsus septicemia in a previously healthy woman. Annals of Emergency Medicine 1991, 20: 93–94.PubMedGoogle Scholar
  13. 13.
    Gallen IW, Ispahani P: FulminantCapnocytophaga canimorsus (DF-2) septicaemia. Lancet 1991, 337: 308.Google Scholar
  14. 14.
    Malnick H, Adhami ZN, Galloway A: Isolation and identification ofCapnocytophaga canimorsus (DF-2) from blood culture. Lancet 1991, 338: 384.Google Scholar
  15. 15.
    Ndon JA:Capnocytophaga canimorsus septicemia caused by a dog bite in a hairy cell leukemia patient. Journal of Clinical Microbiology 1992, 30: 211–213.PubMedGoogle Scholar
  16. 16.
    Pletschette M, Köhl J, Kuipers J, Schmidt RE: OpportunisticCapnocytophaga canimorsus infection. Lancet 1992, 339: 308.Google Scholar
  17. 17.
    Clarke K, Devonshire D, Veitch A, Bellomo R, Parkin G: Dog-bite inducedCapnocytophaga canimorsus septicaemia. Australian and New Zealand Journal of Medicine 1992, 22: 86–87.PubMedGoogle Scholar
  18. 18.
    Bateman JM, Rainford DJ, Masterton RG:Capnocytophaga canimorsus infection and acute renal failure. Journal of Infection 1992, 25: 112–114.PubMedGoogle Scholar
  19. 19.
    Scarlett JD, Williamson HG, Dadson PJ, Fasset R, Peel MM: A syndrome resembling thrombotic thrombocytopenic purpura associated withCapnocytophaga canimorsus septicemia. American Journal of Medicine 1991, 90: 127–128.PubMedGoogle Scholar
  20. 20.
    Mahrer S, Raik E:Capnocytophaga canimorsus septicemia associated with cat scratch. Pathology 1992, 24: 194–196.PubMedGoogle Scholar
  21. 21.
    Carpenter PD, Heppner BT, Gnann JW: DF-2 bacteremia following cat bites. Report of two cases. American Journal of Medicine 1987, 82: 621–623.PubMedGoogle Scholar
  22. 22.
    Kristensen KS, Winthereik M, Rasmussen ML:Capnocytophaga canimorsus infection after dog-bite. Lancet 1991, 337: 849.Google Scholar
  23. 23.
    Chambers GW, Westblom TU: Pleural infection caused byCapnocytophaga canimorsus, formerly CDC group DF-2. Clinical Infectious Diseases 1992, 15: 325–326.PubMedGoogle Scholar
  24. 24.
    Brenner DJ, Hollis DG, Fanning GR, Weaver RE:Capnocytophaga canimorsus sp. nov. (formerly CDC group DF-2), a cause of septicemia following dog bite, andC. cynodegmi sp. nov., a cause of localized wound infection following dog bite. Journal of Clinical Microbiology 1989, 27: 231–235.PubMedGoogle Scholar
  25. 25.
    Verghese A, Hamati F, Berk S, Franzus B, Berk S, Smith K: Susceptibility of dysgonic fermenter 2 to antimicrobial agents in vitro. Antimicrobial Agents and Chemotherapy 1988, 32: 78–80.PubMedGoogle Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgese Hschaft mbH 1995

Authors and Affiliations

  • M. Valtonen
    • 1
  • A. Lauhio
    • 2
  • P. Carlson
    • 3
  • J. Multanen
    • 1
  • A. Sivonen
    • 4
  • M. Vaara
    • 4
  • J. Lähdevirta
    • 2
  1. 1.Department of MedicineHelsinki University Central HospitalHelsinkiFinland
  2. 2.Department of MedicineAurora HospitalHelsinkiFinland
  3. 3.Department of MicrobiologyAurora HospitalHelsinkiFinland
  4. 4.Department of Bacteriology and ImmunologyUniversity of HelsinkiHelsinkiFinland

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