Histological and electron-microscopic examinations of collagenous connective tissue of the non-pregnant cervix, the pregnant cervix, and the pregnant prostaglandin-treated cervix
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The histological appearance of the prostaglandin-pretreated cervix of early pregnancy (8–13 weeks) showed the changes found in the pregnant cervix at term. Electron microscopy showed collagen fibrils of normal periodicity (640 Å) and also collagen degradation products. Evidence of splitting of collagen fibrils could only be seen with light microscopy.
Key wordsCervix softening Prostaglandins Collagen degradation products Histology
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