Journal of Molecular Evolution

, Volume 27, Issue 3, pp 250–260

Molecular evolution among someDrosophila species groups as indicated by two-dimensional electrophoresis

  • Greg S. Spicer

DOI: 10.1007/BF02100081

Cite this article as:
Spicer, G.S. J Mol Evol (1988) 27: 250. doi:10.1007/BF02100081


The evolutionary and phylogenetic relationships of sevenDrosophila species groups (represented byD. melanogaster, D. mulleri, D. mercatorum, D. robusta, D. virilis, D. immigrans, D. funebris, andD. melanica) were investigated by the use of two-dimensional electrophoresis. The resulting phylogeny is congruent with the current views of evolution among these groups based on morphological characters and immunological distances. Previous studies indicated that the ability of one-dimensional electrophoresis to resolve relationships between distantly related taxa extended to about the Miocene [25 million years (Myr) ago], but the present study demonstrates that two-dimensional electrophoresis is a useful indicator of phylogeny even back to the Paleocene (65 Myr ago). In addition, two-dimensional electrophoresis is shown to be a useful technique for detecting slowly evolving structural proteins such as actins and tropomyosins.

Key words

Molecular evolution Two-dimensional electrophoresis Drosophila systematics Phylogenetic analysis Molecular clocks Actin Tropomyosin 

Copyright information

© Springer-Verlag New York Inc 1988

Authors and Affiliations

  • Greg S. Spicer
    • 1
    • 2
  1. 1.Division of Biological and Medical ResearchArgonne National LaboratoryArgonneUSA
  2. 2.Committee on Evolutionary BiologyUniversity of ChicagoChicagoUSA
  3. 3.Linus Pauling InstitutePalo AltoUSA

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