Current Microbiology

, Volume 21, Issue 4, pp 229–231 | Cite as

Oxidation of dibenzothiophene byCunninghamella elegans

  • Donald L. Crawford
  • Rajinder K. Gupta


The metabolism of dibenzothiophene (DBT) by the catabolically versatile fungusCunninghamella elegans (ATCC 36112) was investigated. This fungus has been previously shown to metabolize polycyclic aromatic hydrocarbons including nitropolycyclic aromatics, but has not been shown to metabolize DBT. The results show thatC. elegans oxidizes DBT to its corresponding DBT-5 oxide and then to DBT-sulfone, without the formation of any biphenyl intermediates.


Oxidation Hydrocarbon Polycyclic Aromatic Hydrocarbon Aromatic Hydrocarbon Biphenyl 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Literature Cited

  1. 1.
    Cerniglia CE, White GL, Heflich RH (1985) Fungal metabolism and detoxification of polycyclic aromatic hydrocarbons. Arch Microbiol 143:105–110Google Scholar
  2. 2.
    Cerniglia CE, Freeman JP, White GL, Heflich RH, Miller DW (1985) Fungal metabolism and detoxification of the nitropolycyclic aromatic hydrocarbon 1-nitropyrene. Appl Environ Microbiol 50:649–655Google Scholar
  3. 3.
    Cerniglia CE, Campbell WL, Freeman JP, and Evans FE (1989) Identification of a novel metabolite in phenanthracene metabolism by the fungusCunninghamella elegans. Appl Environ Microbiol 55:2275–2279Google Scholar
  4. 4.
    Ensley Jr BD (1984) Microbial metabolism of condensed thiophenes. In: Gibson DT (ed), Microbial degradation of organic compounds. New York: Marcel Dekker, Inc., pp 309–317Google Scholar
  5. 5.
    Finnerty WR, Robinson M (1986) Microbial desulfurization of fossil fuels. A review. Biotechnol Bioeng Symp 16:205–221Google Scholar
  6. 6.
    Kargi F, Robinson JM (1984) Microbial oxidation of dibenzothiophene by the thermophilic organismSulfolobus acidocaldarius. Biotech Bioeng 26:687–690Google Scholar
  7. 7.
    Kilbane J (1989) Desulfurization of coal: the microbial solution. Trends Biotechnol 7:97–101Google Scholar
  8. 8.
    Kilbane JR, Beilaga BA (1989) Microbial removal of organic sulfur from coal, a molecular genetic approach. IGT Symp on Gas, Oil, Coal and Environmental Biotechnology, New Orleans, USA, Dec. 11–13, 1989Google Scholar
  9. 9.
    Knecht AT (1961) Thesis dissertation, Louisiana State University, Order No. 621235Google Scholar
  10. 10.
    Kodama K, Umehera K, Shimizu K, Nakatini S, Minoda Y, Yamada K (1973) Identification of products from dibenzothiophene and its proposed oxidation pathway. Agric Biol Chem 37:45–50Google Scholar
  11. 11.
    Laborde AL, Gibson DT (1977) Metabolism of dibenzothiophene by aBeijerinckia species. Appl Environ Microbiol 34:783–790Google Scholar
  12. 12.
    Malik KA (1978) Microbial removal of organic sulfur from crude oil and the environment: Some new perspectives. Process Biochem 13:10–12Google Scholar
  13. 13.
    Monticello DJ, Bakker D, Finnerty WR (1985) Plasmid mediated degradation of dibenzothiophene byPseudomonas species. Appl Environ Microbiol 49:756–760Google Scholar
  14. 14.
    Mormile MR, Atlas RM (1988) Mineralization of the DBT biodegradation products, 3-hydroxy-2-formyl benzothiophene and dibenzothiophene sulfone. Appl Environ Microbiol 54:3183–3184Google Scholar
  15. 15.
    Mormile MR, Atlas RM (1989) Biotransformation of dibenzothiophene to dibenzothiophene sulfone byPseudomonas putida. Can J Microbiol 35:603–605Google Scholar
  16. 16.
    Olgwe CA (1988) Microbial desulfurization of coal. Fuel 67:451–458Google Scholar
  17. 17.
    Sariaslani FS (1989) Microbial enzymes for oxidation of organic molecules. Crit Rev Biotechnol 9:171–257Google Scholar

Copyright information

© Springer-Verlag New York Inc. 1990

Authors and Affiliations

  • Donald L. Crawford
    • 1
  • Rajinder K. Gupta
    • 1
  1. 1.Department of Bacteriology and Biochemistry, Institute for Molecular and Agricultural Genetic EngineeringUniversity of IdahoMoscowUSA

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