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Digestive Diseases and Sciences

, Volume 39, Issue 9, pp 1985–1993 | Cite as

Hepatoduodenal bile transit in cholecystectomized subjects

Relationship with sphincter of oddi function and diagnostic value
  • Enrico Corazziari
  • Michele Cicala
  • Fortunée Irene Habib
  • Francesco Scopinaro
  • Fausto Fiocca
  • Nadia Pallotta
  • Andrea Viscardi
  • Alberto Vignoni
  • Aldo Torsoli
Pancreatic And Biliary Disorders

Abstract

The hepatic hilum-duodenum transit time (HHDT) was evaluated in cholecystectomized subjects to assess its relationship with the motor function of the sphincter of Oddi (SO) and its diagnostic accuracy in the detection of SO dysfunction. The study was performed in asymptomatic controls and symptomatic patients with SO dysfunction before and after sphincterotomy. HHDT showed a direct correlation with manometric SO maximal basal pressure (r=0.77;P<0.001) but not with SO phasic activity. In sphincterotomized subjects HHDT did not differ from that of the asymptomatic subjects, and HHDT, which was prolonged before sphincterotomy, normalized after sphincterotomy. HHDT had a 100% specificity and an 83% sensitivity in diagnosing SO dysfunction when compared to SO manometry. In conclusion, the cholescintigraphic HHDT is mainly related to the SO maximal basal pressure, presenting an elevated specificity and a satisfactory sensitivity in the diagnosis of SO dysfunction in cholecystectomized subjects.

Key words

bile flow cholescintigraphy sphincter of Oddi dysfunction motor activity 

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Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • Enrico Corazziari
    • 1
  • Michele Cicala
    • 1
  • Fortunée Irene Habib
    • 1
  • Francesco Scopinaro
    • 1
  • Fausto Fiocca
    • 1
  • Nadia Pallotta
    • 1
  • Andrea Viscardi
    • 1
  • Alberto Vignoni
    • 1
  • Aldo Torsoli
    • 1
  1. 1.From the Cattedra di Gastroenterologia I, Clinica Medica II; Sezione Medicina Nucleare, DPT Medicina Sperimentale, and II Clinica ChirurgicaUniversità “La Sapienza,”RomeItaly

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