European Journal of Pediatrics

, Volume 154, Issue 8, pp 658–661 | Cite as

Floating-Harbor syndrome: description of a further patient, review of the literature, and suggestion of autosomal dominant inheritance

  • D. Lacombe
  • M. A. Patton
  • C. Elleau
  • J. Battin
Original Paper

Abstract

Abstract

The Floating-Harbor syndrome is a growth retardation syndrome with delayed bone age, speech development, and typical facial features. The face is triangular with deep-set eyes, long eyelashes, bulbous nose, wide columella, short philtrum, and thin lips. We present an additional patient and review 16 cases from the literature. The possible phenotype in the patient's mother suggests a dominant mode of inheritance for the syndrome.

Conclusion

The Floating Harbor syndrome is a growth deficiency syndrome characterized by proportionate short stature, characteristic face and delayed speech development. Inheritance is possibly autosomal dominant.

Key words

Floating-Harbor syndrome Growth retardation Dysmorphology Genetics 

Abbreviation

FHS

Floating Harbor syndrome

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Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • D. Lacombe
    • 1
  • M. A. Patton
    • 2
  • C. Elleau
    • 3
  • J. Battin
    • 1
  1. 1.Department of Paediatric GeneticsPellegrin-Children's HospitalBordeaux CédexFrance
  2. 2.S. W. Thames Regional Genetics ServiceSt George's HospitalLondonUK
  3. 3.Department of PaediatricsCHG Mont-de-MarsanFrance

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