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Pharmaceutisch Weekblad

, Volume 9, Supplement 1, pp S68–S71 | Cite as

The use of cipfofloxacin in the treatment of patients with cystic fibrosis

  • P. J. Van Den Broek
  • W. Bakker
  • H. Mattie
  • C. Van Gulpen
Article
  • 10 Downloads

Abstract

The use of ciprofloxacin for the treatment of pulmonary infection in cystic fibrosis patients was investigated.

Therapy was successful in six patients and unsuccessful in three patients. In one patient therapy had to be stopped because serum transaminase levels showed a 5- to 8- fold increase. During therapy resistance developed inHaemophilus influenzae, Staphylococcus aureus andPseudomonas aeruginosa.

Key words

Ciprofloxacin Cystic fibrosis 

References

  1. 1.
    Hodson ME, Roberts CM, Butland RJA, Smith MJ, Batten JC. Oral ciprofloxacin compared with conventional intravenous treatment forPseudomonas aeruginosa infections in adults with cystic fibrosis. Lancet 1987;i:235–7Google Scholar
  2. 2.
    Scully BE, Neu HC, Parry MF, Mandell W. Oral ciprofloxacin therapy of infections due toPseudomonas aeruginosa. Lancet 1986;i:819–22.Google Scholar

Copyright information

© Bohn, Scheltema & Holkema 1987

Authors and Affiliations

  • P. J. Van Den Broek
    • 1
  • W. Bakker
    • 2
  • H. Mattie
    • 1
  • C. Van Gulpen
    • 1
  1. 1.Department of Infectious DiseasesUniversity Hospital Building 1, C5-PRC LeidenThe Netherlands
  2. 2.Department of Pulmonary DiseasesUniversity Hospital Building 1, C5-PRC LeidenThe Netherlands

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