European Journal of Pediatrics

, Volume 154, Issue 5, pp 378–380 | Cite as

Acute transverse myelitis caused by ECHO virus type 18 infection

  • S. Takahashi
  • A. Miyamoto
  • J. Oki
  • H. Azuma
  • A. Okuno
Infectious Diseases Original Paper


a 14-year-old boy developed acute quadriplegia, associated with sensory impairment and bowel and urinary dysfunction. MRI of the cervical cord showed diffuse increased signal intensity on T2-weighted images with gadolinium-diethylenetriamine penta-acetic acid enhancement. Based on the clinical presentation and MRI findings, the diagnosis of acute transverse myelitis was made. Enterovirus RNA was amplified from CSF by the reverse transcriptase-polymerase chain reaction. Serum neutralizing antibody to ECHO virus type 18 rose from 1/4 on admission to 1/16 2 months later.


This is the first reported case of acute transverse myelitis caused by ECHO virus type 18 infection.

Key words

Acute transverse myelitis MRI ECHO virus type 18 Reverse transcriptase Polymerase chain reaction 



acute transverse myelitis


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Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • S. Takahashi
    • 1
  • A. Miyamoto
    • 1
  • J. Oki
    • 1
  • H. Azuma
    • 1
  • A. Okuno
    • 1
  1. 1.Department of PaediatricsAsahiwaka Medical CollegeAsahikawaJapan

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