Clinical Rheumatology

, Volume 3, Issue 2, pp 253–258 | Cite as

A destructive arthropathy following Chikungunya virus arthritis — a possible association

  • S. W. Brighton
  • I. W. Simson
Case Report


Chikungunya virus arthritis is an acute severe polyarthritis following upon the bite of infected mosquitoes in endemic areas. With rapid air transport an increasing number of tourists are being exposed to potential infection. Whether tourists returning home in the incubation viremic stage can infect local mosquito populations in their home countries is unknown. Most cases recover from the severe joint pains within several weeks but up to 12% retain some residual joint symptoms for years. A case report is given of probable Chikungunya arthritis progressing to joint destruction before ultimately subsiding after 15 years leaving a sequela of destroyed metatarsal heads and late osteoarthritic changes in the ankles.

Key words

Chikungunya Infection Virus Arthritis Joint Erosions 


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  1. 1.
    McIntosh, B.M. In the epidemiology of arthropod-bone viruses in South Africa. D.Sc Thesis, University of Pretoria 1980, Ch 7.Google Scholar
  2. 2.
    Robinson, M.C. An epidemic of virus disease in Southern Province Tanganyika Territory in 1952 — 53. Clinical features, Trans R Soc Trop Med Hyg, 1955, 49, 1, 28–32.CrossRefPubMedGoogle Scholar
  3. 3.
    Lumsden, W.H.R. An epidemic of virus disease in Southern Province Tanganyika Territory in 1952–53. General description and epidemiology. Trans R Soc Trop Med Hyg, 1955, 49, 1, 33–57.CrossRefPubMedGoogle Scholar
  4. 4.
    Gear, J. The occurrence of a Dengue — like fever in the North Eastern Transvaal. Clinical features and isolation of virus. S Afr Med J, 1957, 31, 253–257.PubMedGoogle Scholar
  5. 5.
    Roger, L.M. An outbreak of suspected Chikungunya fever in Northern Rhodesia. S Afr J, 1961, 35, 126–128.Google Scholar
  6. 6.
    McIntosh, B.M., Harwin, R.M., Paterson, H.E., Westwater, M.L. An epidemic of Chikungunya in South Eastern Rhodesia. Cent Afr J Med, 1963, 9, 351–359.Google Scholar
  7. 7.
    Nummannitya, S., Halstead, S.B., Cohen, S.N., Margrotta, M.R. Dengue and Chikungunya virus infection in man in Thailand 1962–1964. Am J Trop Med Hyg, 1969, 18, 954–971.PubMedGoogle Scholar
  8. 8.
    Deller, J.J., Russel, P.K. Chikungunya disease. Am J Trop Med Hyg, 1968, 17, 107–111.PubMedGoogle Scholar
  9. 9.
    De Ranitz, C.M., Myers, R.M., Varkey, M.J., Isaac, Z.H., Carey, D.E. Clinical impressions of Chikungunya in Vellore gained from study of adult patients. Indian J Med Res, 1965, 53, 756–763.PubMedGoogle Scholar
  10. 10.
    Fourie, E.D., Morrison, J.G.L. Rheumatoid arthritic syndrome after Chikungunya fever. S Afr Med J, 1979, 56, 130–132.PubMedGoogle Scholar
  11. 11.
    Kennedy, A.C., Fleming, J., Solomon, L. Chikungunya viral Arthropathy. A clinical description. J Rheumatol, 1980, 7, 231–236.PubMedGoogle Scholar
  12. 12.
    Brighton, S.W., Prozesky, O.W., De la Harpe, A.L. Chikungunya virus infection. A retrospective study of 107 cases. S Afr Med J, 1983, 63, 313–315.PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • S. W. Brighton
    • 1
  • I. W. Simson
    • 1
  1. 1.Department of Rheumatology, Department of Anatomical pathologyUniversity of Pretoria Medical SchoolPretoriaSouth Africa

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