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International Ophthalmology

, Volume 13, Issue 1–2, pp 109–112 | Cite as

Therapeutic value of citicoline in the treatment of glaucoma (computerized and automated perimetric investigation)

  • J. Pecori Giraldi
  • M. Virno
  • G. Covelli
  • G. Grechi
  • F. De Gregorio
Article

Abstract

The favourable neurotrophic effects obtained by means of the intramuscular administration of citicoline, one of the intermediate compounds of phospholipids, on the visual field of patients suffering from open-angle glaucoma are referred. The drug was administered at the dose of 1 gm for ten consecutive days. Visual field was examined by means of central computerized perimetry and automated perimetry. All patients had well controlled intraocular pressure through beta-blockers, but presented characteristic glaucomatous perimetric defects. It is suggested that citicoline might be administered as a useful complement to conventional hypotensive therapy, since it acts positively on the glaucomatous optic nerve damage.

Key words

citicoline neurotrophic action central computerized perimetry automated perimetry glaucoma 

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References

  1. 1.
    Accornero N, Berardelli A, Cruccu G, Manfredi M. Computerized video-screen perimetry. Arch Ophthalmol 102: 40, 1984PubMedGoogle Scholar
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    Taverniti L, Accornero N. Topographie automatique du champs visuel centrale (entre 20°) chez des patients glaucomateux. Bull et Mém Soc Fr Ophtal 95: 571, 1983Google Scholar
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    Virno M, Pecori-Giraldi J, Grechi G, Covelli G, De Gregorio F. Valore terapeutico della citicolina nel paziente glaucomatoso (Indagine perimetrica computerizzata). Meeting of ‘The Associazione Italiana per lo studio del glaucoma’. Rapallo, March 1988Google Scholar

Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • J. Pecori Giraldi
    • 1
  • M. Virno
    • 1
  • G. Covelli
    • 1
  • G. Grechi
    • 1
  • F. De Gregorio
    • 1
  1. 1.Clinica Oculistica IUniversita' Di Roma ‘La Sapienza’RomaItalia

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