European Journal of Pediatrics

, Volume 150, Issue 11, pp 776–779 | Cite as

Beta-haemolytic non-group A streptococci and pharyngitis: A case-control study

  • N. Cimolai
  • B. J. Morrison
  • L. MacCulloch
  • D. F. Smith
  • J. Hlady
Infectious Diseases


A case-control study was conducted to examine the association of beta-haemolytic non-group A streptococci and pharyngitis in a paediatric population (n=502). No association could be found between disease and traditional Lancefield groups B, C, F, or G. When the analysis included the clustering of genetically related subgroups from different Lancefield groups, an association was evident for moderate and heavy quantitations of beta-haemolytic “large colony” group C and G streptococci (Streptococcus equisimilis and human biotypes of large colony group G streptococci) (p=0.021). This study further defines a subset of the beta-haemolytic non-group A streptococci that merit recognition by both the laboratory and physician.

Key words

Pharyngitis Streptococci Case-control study 



beta haemolytic non-group A streptococci


Voges-Proskauer test


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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • N. Cimolai
    • 1
    • 4
  • B. J. Morrison
    • 2
  • L. MacCulloch
    • 4
  • D. F. Smith
    • 3
  • J. Hlady
    • 3
  1. 1.Division of Medical Microbiology, Department of PathologyUniversity of British ColumbiaVancouverCanada
  2. 2.Departments of Health Care and EpidemiologyUniversity of British ColumbiaVancouverCanada
  3. 3.Department of PaediatricsUniversity of British ColumbiaVancouverCanada
  4. 4.Programme of Microbiology, Department of PathologyBritish Columbia's Children's HospitalVancouverCanada

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