Pediatric Radiology

, Volume 24, Issue 5, pp 328–332 | Cite as

Soft tissue signal abnormality associated with eosinophilic granuloma

Correlation of MR imaging with pathologic findings
  • M. Monroc
  • H. Ducou le Pointe
  • S. Haddad
  • P. Josset
  • J. P. Montagne


Six patients with eosinophilic granuloma were studied retrospectively in order to correlate the MRI appearances with the pathology. Ages ranged from 2 years 6 months to 11 years. The bones involved were the humerus, ulna, radius, femur, clavicle and ilium. Plain films, MRI and pathology specimens were obtained. A lytic lesion with indistinct margins, endosteal erosions and periosteal reaction was seen in all cases on plain radiographs. Bone marrow signal was decreased on T1-weighted images and increased on T2-weighted images throughout the bony lesion in all cases. T2-weighted images showed extensive soft-tissue abnormalities suggesting inflammatory changes in four cases. In two cases abnormalities were limited. Extensive changes correlated histologically with an early phase lesion. Localized minor changes were associated with a mid-phase lesion. Inflammatory soft-tissue changes could be associated with eosinophilic granuloma. The size of the soft tissue mass correlated well with the activity of the bony lesion.


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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • M. Monroc
    • 1
  • H. Ducou le Pointe
    • 1
  • S. Haddad
    • 1
  • P. Josset
    • 2
  • J. P. Montagne
    • 1
  1. 1.Department of Pediatric RadiologyHôpital d'Enfants Armand-TrousseauParis Cedex 12France
  2. 2.Department of Anatomo-PathologyHôpital d'Enfants Armand-TrousseauParis Cedex 12France

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