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Experientia

, Volume 36, Issue 1, pp 72–74 | Cite as

Opposite effects ofβ-adrenoceptor stimulation and 8-bromo-cyclic AMP on potassium efflux in mammalian heart muscle

  • H. Nawrath
  • I. Blei
  • R. Gegner
Specialia

Summary

β-adrenoceptor stimulation by isoprenaline increases the potassium efflux in beating guinea-pig atria. This effect is not mimicked by 8-bromo-cyclic AMP, a cyclic AMP analogue which exerts a positive inotropic effect in this preparation.

Keywords

Potassium Opposite Effect Heart Muscle Isoprenaline Positive Inotropic Effect 

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Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • H. Nawrath
    • 1
  • I. Blei
    • 1
  • R. Gegner
    • 1
  1. 1.Pharmakologisches Institut der Universität MainzMainzGermany

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