Experientia

, Volume 33, Issue 3, pp 398–400 | Cite as

Antagonistic action of E and F series prostaglandins upon mineralocorticoid production by the human adrenal

  • K. V. Honn
  • W. Chavin
Specialia

Summary

At long time intervals, the E and F prostaglandins exert antagonistic effects on aldosterone production in vitro. At short intervals the E prostaglandins tend to mimic the inhibitory effect of the PGF series.

Keywords

Prostaglandin Aldosterone Short Interval Antagonistic Effect Mineralocorticoid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. 1.
    K. V. Honn and W. Chavin, Biochem. biophys. Res. Commun.73, 164 (1976).PubMedGoogle Scholar
  2. 2.
    F. A. Kuehl, Prostaglandins5, 325 (1974).PubMedGoogle Scholar
  3. 3.
    S. A. S. Tait, J. F. Tait and J. E. S. Bradley, Aust. J. exp. Biol. Med. Sci.50, 833 (1972).PubMedGoogle Scholar
  4. 4.
    P. J. Hornsby, M. J. O'Hare and A. M. Neville, Endocrinology95, 1240 (1974).PubMedGoogle Scholar
  5. 5.
    C. S. Price, J. L. Ruse and J. C. Laidlaw, Can. J. Physiol. Pharmac.53, 531 (1975).Google Scholar
  6. 6.
    T. Saruta and N. M. Kaplan, J. Clin. Invest.51, 2246 (1972).PubMedGoogle Scholar
  7. 7.
    J. R. Blair-West, J. P. Coghlan, D. A. Denton, J. W. Funder, B. A. Scuggins and R. P. Wright, Endocrinology88, 367 (1971).PubMedGoogle Scholar
  8. 8.
    J. K. McKenzie and J. A. Clements, J. clin. Endocr. Metab.38, 622 (1974).PubMedGoogle Scholar
  9. 9.
    K. V. Honn and W. Chavin, Analyt. Biochem.68, 230 (1975).PubMedGoogle Scholar
  10. 10.
    R. P. Rubin, B. Sheid, R. McCauley and S. G. Laychock, Endocrinology95, 370 (1974).PubMedGoogle Scholar
  11. 11.
    D. P. Penney, J. Olson, G. V. Marinetti, S. Vaala and K. Averill, Z. Zellforsch.146, 309 (1973).PubMedGoogle Scholar
  12. 12.
    D. P. Penney, J. Olson and K. Averill, Z. Zellforsch.146, 297 (1973).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • K. V. Honn
    • 1
  • W. Chavin
    • 1
  1. 1.Departments of Radiology and BiologyWayne State UniversityDetroitUSA

Personalised recommendations