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Evaluation of an antigen-capture enzyme immunoassay for rapid diagnosis ofMycoplasma pneumoniae infection

  • M. Kleemola
  • R. Räty
  • J. Karjalainen
  • W. Schuy
  • B. Gerstenecker
  • E. Jacobs
Notes

Abstract

A new enzyme immunoassay (EIA; Enzygost) for rapid detection ofMycoplasma pneumoniae antigen was evaluated in 51 young adults with acute respiratory infection. The EIA results using sputa and nasopharyngeal aspirates were compared with those of serological antibody tests, culture and a DNA probe. In sputum the sensitivity of the EIA ranged from 40 % to 81 % and the specificity from 64 % to 100 %, depending on the reference method. In nasopharyngeal aspirates the sensitivity was well below 20 %, but the test was nearly 100 % specific.

Keywords

Internal Medicine Young Adult Respiratory Infection Enzyme Immunoassay Reference Method 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1993

Authors and Affiliations

  • M. Kleemola
    • 1
  • R. Räty
    • 1
  • J. Karjalainen
    • 2
  • W. Schuy
    • 3
  • B. Gerstenecker
    • 4
  • E. Jacobs
    • 4
  1. 1.National Public Health InstituteHelsinkiFinland
  2. 2.Central Military HospitalHelsinkiFinland
  3. 3.Behringwerke AGMarburgGermany
  4. 4.Institute for Medical Microbiology and HygieneUniversity HospitalFreiburgGermany

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