, Volume 32, Issue 5, pp 659–660

Histamine as an extremely potent releaser of vasopressin in the rat

  • J. Dogterom
  • Tj. B. van Wimersma Greidanus
  • D. De Wied


Intraperitoneal and intraventricular injection of histamine induces a very fast and high elevation of vasopressin in rat plasma as determined by radioimmunoassay. The effects are dose and time related. The intraventricular injection is more effective with regard to time and dose than the intraperitoneal injection.


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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • J. Dogterom
    • 1
    • 2
  • Tj. B. van Wimersma Greidanus
    • 1
    • 2
  • D. De Wied
    • 1
    • 2
  1. 1.Netherlands Central Institute for Brain ResearchAmsterdam-0The Netherlands
  2. 2.Rudolf Magnus Institute for Pharmacology, Medical FacultyUniversity of UtrechtUtrechtThe Netherlands

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