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Experientia

, Volume 32, Issue 5, pp 645–647 | Cite as

The effects of tryptophol on immune responses and its implications toward trypanosome-induced immunosuppression

  • S. B. Ackerman
  • J. R. Seed
Article

Summary

Daily administrations of tryptophol to laboratory rodents resulted in significantly depressed antibody production to heterologous red blood cell challenge, but did not alter cellular-mediated responses to oxazalone. These results suggest that trypanosome-produced tryptophol may account for the immunodepression observed during trypanosomiasis.

Keywords

Immune Response Blood Cell Antibody Production Daily Administration Trypanosomiasis 
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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • S. B. Ackerman
    • 1
  • J. R. Seed
    • 1
  1. 1.Laboratory of Parasitology, Department of BiologyTulane UniversityNew OrleansUSA

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