Pulmonary defence mechanisms: Damage and repair
- 48 Downloads
In this article pulmonary defence mechanisms and factors causing (progressive) tissue damage in some common settings of lower respiratory tract infections are dealt with. Opportunities for intervention are different, considering the proper cause. Passive immunization is appropriate in case of immune deficiency and active immunization applies to a series of clinical conditions in which the immune system for the greater part is intact but other defence mechanisms are impaired. Besides antibiotic treatment, anti-inflammatory therapy is considered beneficial, anticipating progressive tissue damage.
KeywordsDefence mechanisms Drug therapy Infection Inflammation Lung
Unable to display preview. Download preview PDF.
- 1.Van der Baan S, Veerman AJP, Weltevreden EF, Feenstr L. Kartagener's syndrome: clinical symptoms and laboratory studies. Eur J Dis 1983;64(Suppl 127):91–5.Google Scholar
- 3.Bice DE. Induction of antibody responses after localized immunization. Bull Fijnvl Longafw 1987;12:47–53.Google Scholar
- 4.Colby ThV, Chung AC. Patterns of pulmonary fibrosis. Pathol Ann 1986;21:277–309.Google Scholar
- 5.Willems LNA. Antileukoprotease in the human lung. A morphologic study [Dissertation]. Leiden: Leiden University, 1988.Google Scholar
- 6.Corrin B. Epithelial and endothelial cells in alveolar damage and repair. Bull Fijnvl Longafw 1987;12:64–7.Google Scholar
- 7.Basset F, Soler P. Connective tissue cells in pulmonary alveolar damage repair. Bull Fijnvl Longafw 1987;12:68–72.Google Scholar
- 8.Döring G, Albus A, Hóiby N. Immunologic aspects of cystic fibrosis. Chest 1988;94(Suppl 2):109s.Google Scholar
- 10.Wevers MD, Casolaro MA, Sellers SE, et al. Replacement therapy for alpha-1-proteinase deficiency associated with emphysema. N Engl J Med 1987:147:166–9.Google Scholar