European Journal of Pediatrics

, Volume 153, Issue 6, pp 416–418 | Cite as

Monitoring steatorrhoea in cystic fibrosis

  • M. De Curtis
  • F. Santamaria
  • P. Ercolini
  • G. Sica
  • V. Bianco
  • F. Ciccimarra
Gastroenterology/Hepatology

Abstract

The aim of the study was the evaluation of the relationship between chemical fat analysis and some more rapid tests proposed to estimate steatorrhoea. Stool collections (72 h) were obtained on 32 occasions in 22 patients with cystic fibrosis and in seven healthy children. A very close relationship was found between faecal fat, as measured by standard chemical methods, and faecal energy (r=0.95,P<0.001). We conclude that the determination of faecal energy, easier to measure than faecal fat, can provide reliable information about the extent of steatorrhoea in cystic fibrosis.

Key words

Steatorrhoea Faecal energy Cystic fibrosis 

Abbreviations

CF

cystic fibrosis

SEE

standard error of estimate

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Benini L, Caliari S, Guidi CG (1989) Near infrared spectrometry for faecal fat measurement: comparison with conventional gravimetric and titrimetric methods. Gut 30:1344–1347PubMedGoogle Scholar
  2. 2.
    Boat TF, Welsh MJ, Beaudet AL (1989) Cystic fibrosis. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds) The metabolic basis of inherited disease, 6th edn. Mc Graw-Hill New York, pp 2649–2680Google Scholar
  3. 3.
    De Curtis M, Senterre J, Rigo J (1986) Estimated and measured energy content of infant formulas. J Pediatr Gastroenterol Nutr 5:746–749PubMedGoogle Scholar
  4. 4.
    Ditchburn RK, Smith AH, Hayter CJ (1971) Use of unabsorbed radioactive marker sybstances in a reassessment of the radioactive trioelin test of fat absorption. J Clin Pathol 24:506–514PubMedGoogle Scholar
  5. 5.
    Durie PR, Pencharz PB (1989) A rational approach to the nutritional care of patients with cystic fibrosis. J Roy Soc Med 82 [Suppl 16]:11–20Google Scholar
  6. 6.
    Fidanza N, Liguori G (1981) Nutrizione umana. Idelson, NapoliGoogle Scholar
  7. 7.
    Holmes GKT, Hill PG (1988) Do we still need to measure faecal fat? BMJ 296:1552PubMedGoogle Scholar
  8. 8.
    Murphy JL, Wootton SA, Bond SA, Jackson AA (1991) Energy content of stools in normal healthy controls and patients with cystic fibrosis. Arch Dis Child 61:495–500Google Scholar
  9. 9.
    Penfold WAF, Keynes WM (1971) Use of a standard fatty meal as a test for fat absorption. Ann Surg 173: 157–163PubMedGoogle Scholar
  10. 10.
    Robinson P (1988) Measuring faecal fat. BMJ 297:289Google Scholar
  11. 11.
    Turner JM, Lawrence S, Fellows IW, Johnson I, Hill PG, Holmes GHT (1987) (14C)-trioelin absorption, a useful test in the diagnosis of malabsorption. Gut 28:694–700PubMedGoogle Scholar
  12. 12.
    Van de Kamer JH, Bokkel Huinink H ten, Weyers HA (1949) Rapid method for the determination of fat in faces. J Biol Chem 177:347–355Google Scholar
  13. 13.
    Zuckerman JL, Zymaris MC, Natelson S (1949) Simple method for the determination of fecal fat and fatty acids. J Lab Clin Med 34:282–286Google Scholar

Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • M. De Curtis
    • 1
    • 2
  • F. Santamaria
    • 1
    • 2
  • P. Ercolini
    • 1
    • 2
  • G. Sica
    • 1
    • 2
  • V. Bianco
    • 1
    • 2
  • F. Ciccimarra
    • 1
    • 2
  1. 1.Department of Paediatrics, Second School of MedicineUniversity of NaplesNaplesItaly
  2. 2.Istituto di Scienze dell'AlimentazioneCNR-AvellinoItaly

Personalised recommendations