Applied Microbiology and Biotechnology

, Volume 25, Issue 2, pp 101–105 | Cite as

Effect of aeration rate and influence of pCO2 in large-scale cultures ofCatharanthus roseus cells

  • Jean Paul Ducos
  • Alain Pareilleux


Catharanthus roseus cells were grown at various aeration rates using normal or CO2-enriched air. Kinetic data showed a detrimental effect of the increase of the gassing rate on the growth characteristics due to CO2 stripping. When the CO2 partial pressure in the culture was maintained at a constant level of 20 mbar, better growth and enhanced conversion yields were obtained.


Partial Pressure Detrimental Effect Aeration Kinetic Data Growth Characteristic 
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Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • Jean Paul Ducos
    • 1
  • Alain Pareilleux
    • 1
  1. 1.Département de Génie Biochimique et Alimentaire, UA-CNRS-No 544Institut National des Sciences AppliquéesToulouse CédexFrance

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