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Pharmaceutisch Weekblad

, Volume 12, Issue 5, pp 190–195 | Cite as

Quantitative determination of particulate contamination in intravenous administration sets

  • E. R. Di Paolo
  • B. Hirschi
  • A. Pannatier
Articles

Abstract

Particle counts were performed on 1,000 intravenous administration sets from ten suppliers on the Swiss market using a HIAC/Royco electronic counter. The following main conclusions may be drawn from the results of this study:
  • the small particles were the most numerous, regardless of the type of set;

  • the differences in the counts obtained for the different suppliers' sets tended to level off for particles larger than 10μm;

  • the drip chamber and latex connector may be two important sources of particles;

  • the particulate contamination from the sets is relatively low compared with the amount of particles contained in the parenteral solutions.

Keywords

Equipment and supplies Infusions, parenteral Particle size Particulate matter 

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Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1990

Authors and Affiliations

  • E. R. Di Paolo
    • 1
  • B. Hirschi
    • 1
  • A. Pannatier
    • 1
  1. 1.Service of PharmacyCentre Hospitalier Universitaire Vaudois (C.H.U.V.)LausanneSwitzerland

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