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Pharmaceutisch Weekblad

, Volume 8, Issue 1, pp 85–88 | Cite as

Bioavailability of orally administered zinc, using Taurizine

  • F. J. Duisterwinkel
  • B. G. Wolthers
  • B. J. Koopman
  • F. A. J. Muskiet
  • W. Van der Slik
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  • 27 Downloads

Abstract

Zinc aspartate equivalent to 50 mg of elementary zinc, orally administered to seven normal healthy male volunteers in an enteric-coated tablet (Taurizine®), gave no significantly increased plasma zinc levels, neither when this drug was taken in a fasting state nor during a lunch. The formulation of this tablet seems to obstruct the absorption of zinc.

Key words

Absorption Enteric-coated tablet Plasma levels Taurine Urine excretion Zinc aspartate 

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Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1986

Authors and Affiliations

  • F. J. Duisterwinkel
    • 1
  • B. G. Wolthers
    • 1
  • B. J. Koopman
    • 1
  • F. A. J. Muskiet
    • 1
  • W. Van der Slik
    • 1
  1. 1.Central Laboratory for Clinical ChemistryUniversity HospitalRB GroningenThe Netherlands

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