Place of quinolones in the therapeutic armoury
Quinolones in Perspective
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Abstract
On the basis of antimicrobial activity, resistance development, pharmacokinetics, side effects and pre-clinical results, the applicability of the quinolones ciprofloxacin, enoxacin, norfloxacin, ofloxacin and pefloxacin is assessed. These quinolones seem especially useful in infections in hospitalized patients, in gonococcal infections and in urinary tract infections. Also salmonellosis and shigellosis might be indications for quinolones.
Key words
Drug evaluation, preclinical Drug resistance Pharmacokinetics Quinolones Side effectsReferences
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© Royal Dutch Association for Advancement of Pharmacy 1986