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Pharmaceutisch Weekblad

, Volume 14, Issue 6, pp 357–359 | Cite as

Comparison of costs linked to the preparation and administration of fluorouracil as a continuous infusion based on three techniques

  • P. Larrouturou
  • J. L. Rebischung
  • M. C. Taugourdeau
  • J. Sauvaget
  • J. Huchet
Practice/Case Reports
  • 23 Downloads

Abstract

The approach in treatment in medical oncology and particularly in the management of solid tumours has to integrate — at least — two targets: the enhancement of therapeutic efficacy, and the respect of global budget assigned to health. Different teams are implicated in such an approach and especially physicians and pharmacists. We decided to conduct a comparative study of three techniques of administering drugs as a continous infusion. We analysed time and materials required for the preparation in the centralized preparation unit, and for dispensing and nursing in the health units. The use of programmable pumps (CADD-1) leads to overall saving costs of 27 to 40% compared to administration by means of an infusion bag or a motor-drive syringe.

Keywords

Cost and cost analysis Drug compounding Equipment and supplies Fluorouracil Infusions, parenteral 

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References

  1. 1.
    Johnson MS, Pesko LJ, Wood CF, Reinders TP. Cost and acceptability of three syringe-pump infusion systems. Am J Hosp Pharm 1990;47:1794–8.PubMedGoogle Scholar
  2. 2.
    Larrouturou P, Rebischung J-L, Taugourdeau M-C, Sauvaget J, Huchet J. Comparison of costs for preparation and administration of fluorouracil (5FU) in continuous infusion by three different methods. In: Carstens G, Shafford A, eds. Topics in cancer care. Proceedings of the second Interdisciplinary Workshop of Handling Cytotoxic Drugs. Hannover: Schlüterse Verlagsanstalt und Druckerei, 1990.Google Scholar
  3. 3.
    Taylor SG IV, Murthy AK, Showel JL, Griem K, Kies MS, Mitaal B, et al. Comparison of toxicity in a randomized trial of sequential vs. simultaneous cisplatin/5-FU infusion and radiation therapy in head and neck cancer [abstract]. In: Leventhal B, ed. Proceedings of the 25th Annual Meeting of the American Society of Clinical Oncology, 1989. Washington: American Society of Clinical Oncology, 1989:abstract 681.Google Scholar

Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1992

Authors and Affiliations

  • P. Larrouturou
    • 1
  • J. L. Rebischung
    • 2
  • M. C. Taugourdeau
    • 1
  • J. Sauvaget
    • 2
  • J. Huchet
    • 1
  1. 1.Centralized Preparation Unit, Department of PharmacySaint-Joseph HospitalParisFrance
  2. 2.Medical Oncology UnitSaint-Joseph HospitalParisFrance

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