Agents and Actions

, Volume 30, Issue 1–2, pp 243–246 | Cite as

Histamine metabolism in diabetic rats

  • W. A. Fogel
  • C. Chmielecki
  • M. Grałek
  • C. Maslinski
Histamine: Metabolism and Cell Proliferation

Abstract

Streptozotocin-induced diabetes in rats has been used to study the effect of insulin deficiency on histamine metabolism. There were significant increases in the amine content in the pancreas and intestine, and a significant drop in intestinal diamine oxidase (DAO) activity. The reduced DAO activity may be of clinical relevance.

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Copyright information

© Birkhäuser Verlag 1990

Authors and Affiliations

  • W. A. Fogel
    • 1
  • C. Chmielecki
    • 1
  • M. Grałek
    • 1
  • C. Maslinski
    • 1
  1. 1.Department of Biogenic AminesPolish Academy of SciencesLodzPoland

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