High incidence of tuberculosis in renal patients

  • M. E. García-Leoni
  • C. Martín-Scapa
  • P. Rodeño
  • F. Valderrábano
  • S. Moreno
  • E. Bouza
Notes

Abstract

The incidence and clinical characteristics of mycobacteriosis in patients attending the nephrology department in a hospital in Madrid, Spain, during a 30-month period were analysed retrospectively. Twenty-two new cases of tuberculosis were detected among 525 patients studied. No cases of clinically significant atypical mycobacteriosis were found. The estimated overall annual incidence of tuberculosis in these patients was 259 cases per 100,000 population, which is much higher than the national annual incidence in Spain of 35 per 100,000 population. Most cases were asymptomatic when diagnosed and extrapulmonary involvement was the rule (86% of all patients). In areas with a high prevalence of tuberculosis, renal patients in high-risk groups (renal transplant recipients, haemodialysis and CAPD patients) should be examined periodically to exclude silent infection.

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References

  1. 1.
    Malhotra KK, Dash SC, Dhawan IK, Bhuyan UN, Gupta A: Tuberculosis and renal transplantation. Observations from an endemic area of tuberculosis. Postgraduate Medical Journal 1986, 62: 359–362.PubMedGoogle Scholar
  2. 2.
    Sasaki S, Akiba T, Suenaga M, Tomura S, Yoshiyama N, Nakagawa S, Shoji T, Sasaoka T, Takeuchi J: Ten year survey of dialysis-associated tuberculosis. Nephron 1979, 24: 141–145.PubMedGoogle Scholar
  3. 3.
    Andrew OT, Schoenfeld PY, Hopewell PC, Humphreys MH: Tuberculosis in patients with end-stage renal disease. American Journal of Medicine 1980, 68: 59–65.PubMedGoogle Scholar
  4. 4.
    Lundin AP, Adler AJ, Berlyne GM, Friedman EA: Tuberculosis in patients undergoing maintenance hemodialysis. American Journal of Medicine 1979, 67: 597–602.PubMedGoogle Scholar
  5. 5.
    Sommers HM, Good RC:Mycobacterium. In: Lennette EH, Balows A, Hausler WJ, Shadomy HJ (ed): Manual of clinical microbiology. American Society for Microbiology, Washington, DC, 1985, p. 216–248.Google Scholar
  6. 6.
    Editorial. Tuberculosis in chronic renal failure. Lancet 1980, i: 909–910.Google Scholar
  7. 7.
    McWhinney N, Khan O, Williams G: Tuberculosis in patients undergoing maintenance haemodyalisis and renal transplantation. British Journal of Surgery 1981, 68: 408–411.PubMedGoogle Scholar
  8. 8.
    Lichtenstein IH, Mac Gregor RR: Mycobacterial infections in renal transplant recipients: report of five cases and review of the literature. Reviews of Infectious Diseases 1983, 5: 216.PubMedGoogle Scholar
  9. 9.
    Peterson PK, Matzke G, Keane WF: Current concepts in the management of peritonitis in patients undergoing continuous ambulatory peritoneal dialysis. Reviews of Infectious Diseases 1987, 9: 604–612.PubMedGoogle Scholar
  10. 10.
    Papadimitriou M, Memmos D, Metaxas P: Tuberculosis in patients on regular haemodialysis. Nephron 1979, 24: 53–57.PubMedGoogle Scholar
  11. 11.
    Rutsky EA, Rostand SG: Mycobacteriosis in patients with chronic renal failure. Archives of Internal Medicine 1980, 140: 57–61.PubMedGoogle Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1990

Authors and Affiliations

  • M. E. García-Leoni
    • 1
  • C. Martín-Scapa
    • 1
  • P. Rodeño
    • 1
  • F. Valderrábano
    • 2
  • S. Moreno
    • 1
  • E. Bouza
    • 1
  1. 1.Department of Clinical MicrobiologyHospital General “Gregorio Marañón”, Universidad ComplutenseMadridSpain
  2. 2.Department of NephrologyHospital General “Gregorio Marañón”, Universidad ComplutenseMadridSpain

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