Experientia

, Volume 36, Issue 5, pp 601–603

Cellular events in denervated limb stumps ofAmbystoma larvae during re-innervation and subsequent regeneration

  • N. S. Petrosky
  • R. A. Tassava
  • C. L. Olsen
Specialia

Summary

Amputated, denervatedAmbystoma forelimbs undergo cellular dedifferentiation and slight resorption through 12 days post-amputation. Subsequently, as limb stumps become re-innervated, there occur mitosis, blastema formation, and regeneration. The initial increase in the mitotic index in once-denervated limb stumps is closely correlated with the presence of ingrowing nerve fibres.

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References

  1. 2.
    E.G. Butler and O.E. Schotté, J. exp. Zool.88, 307 (1941).CrossRefGoogle Scholar
  2. 3.
    C.S. Thornton, J. exp. Zool.122, 119 (1953).CrossRefGoogle Scholar
  3. 4.
    R.A. Tassava, L.L. Bennett and G.D. Zitnik, J. exp. Zool.190, 111 (1974); A.L. Mescher and R.A. Tassava, Devl. Biol.44, 187 (1975); R.A. Tassava and A.L. Mescher, J. exp. Zool.195, 253 (1976).CrossRefPubMedGoogle Scholar
  4. 5.
    R.A. Tassava and A.L. Mescher, Differentiation4, 23 (1975).CrossRefPubMedGoogle Scholar
  5. 6.
    R.A. Tassava and W.D. McCullough, Am. Zoologist18, 729 (1979).Google Scholar
  6. 7.
    M. Singer, Q. Rev. Biol.27, 162 (1952).CrossRefGoogle Scholar
  7. 8.
    D.J. Kelly and R.A. Tassava, J. exp. Zool.185, 45 (1973).CrossRefPubMedGoogle Scholar
  8. 9.
    P.W. Tank, B.M. Carlson and T.G. Connelly, J. Morph.150, 117 (1976).CrossRefPubMedGoogle Scholar
  9. 10.
    E.P. Samuel, Anat. Rec.116, 511 (1953).CrossRefPubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • N. S. Petrosky
    • 1
  • R. A. Tassava
    • 1
  • C. L. Olsen
    • 1
  1. 1.Developmental Biology Program and Department of ZoologyThe Ohio State UniversityColumbusUSA

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