Clinical programs for clinical research on AIDS: Description of a randomized prospective study of clindamycin versus pyrimethamine for prevention ofToxoplasma gondii infection
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The risk of toxoplasmic encephalitis complicating AIDS appears largely limited to those HIV-infected patients with serologic evidence of pastToxoplasma gondii infection and low CD4 lymphocyte counts. The Community Programs for Clinical Research on AIDS has initiated a randomized, placebo-controlled trial to determine if clindamycin or pyrimethamine prophylactic regimens are effective and safe in preventing toxoplasmic encephalitis.
KeywordsInternal Medicine Clinical Research Encephalitis Clindamycin Lymphocyte Count
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