Isolation ofFrancisella tularensis biovarpalaearctica from human blood

  • A. Tärnvik
  • C. Henning
  • E. Falsen
  • G. Sandström
Notes

Abstract

Francisella tularensis septicemia has previously been reported in the USA, whereFrancisella tularensis biovartularensis (type A) occurs endemically. The present report describes two cases of septicemia caused by the Euro-AsianFrancisella tularensis biovarpalaearctica (type B). The patients lived in an endemic region of Sweden and presented with high fever and pneumonia. Both patients recovered. The ability ofFrancisella tularensis biovarpalaearctica to cause bacteremia has consequences for laboratory safety.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Provenza, J. M., Klotz, S. A., Penn, R. L.: Isolation ofFrancisella tularensis from blood. Journal of Clinical Microbiology 1986, 24: 453–455.Google Scholar
  2. 2.
    Jellison, W. L., Owen, C. R., Bell, J. F., Kohls, G. M.: Tularemia and animal populations: ecology and epizootiology. Wildlife Disease 1961, 17: 1–22.Google Scholar
  3. 3.
    Falsen, E.: Immunodiffusion as an aid in routine identification of uncommon aerobic gram-negative bacteria. In: Leclerc, H. (ed.): Gram-negative bacteria of medical and public health importance: taxonomy, identification, applications. Les éditions de l'Institute National de la Santé et de la Recherche Médicale. Paris, 1983, p. 477–483.Google Scholar
  4. 4.
    Ohara, S., Sato, T., Homma, H.: Serological studies onFrancisella tularensis, Francisella novicida, Yersinia philomiragia andBrucella abortus. International Journal of Systematic Bacteriology 1974, 24: 191–196.Google Scholar
  5. 5.
    Jantzen, E., Berdal, B. P., Omland, T.: Cellular fatty acid composition ofFrancisella tularensis. Journal of Clinical Microbiology 1979, 10: 928–930.Google Scholar
  6. 6.
    Sandström, G., Löfgren, S., Tärnvik, A.: A capsule-deficient mutant ofFrancisella tularensis LVS exhibits enhanced sensitivity to killing by serum but diminished sensitivity to killing by polymorphonuclear leukocytes. Infection and Immunity 1988, 56: 1194–1202.Google Scholar
  7. 7.
    Marchette, N. J., Nicholes, P. S.: Virulence and citrulline ureidase activity ofPasteurella tularensis. Journal of Bacteriology 1961, 82: 26–32.Google Scholar
  8. 8.
    Overholt, E. L., Tigertt, W. D., Kadull, P. J., Ward, M. K., Charkes, N. D., Rene, R. M., Saltzman, T. E., Stephens, M.: An analysis of forty-two cases of laboratory-acquired tularemia. Treatment with broad spectrum antibiotics. American Journal of Medicine 1961, 30: 785–806.Google Scholar
  9. 9.
    Pullen, R. L., Stuart, B. M.: Tularemia. Analysis of 225 cases. Journal of the American Medical Association 1945, 129: 495–500.Google Scholar
  10. 10.
    van Metre, T. E., Kadull, P. J.: Laboratory-acquired tularemia in vaccinated individuals: a report of 62 cases. Annals of Internal Medicine 1959, 50: 621–632.Google Scholar
  11. 11.
    Evans, M. E., Gregory, D. W., Schaffner, W., McGee, Z. A.: Tularemia: a 30-year experience with 88 cases. Medicine 1985, 64: 251–269.Google Scholar
  12. 12.
    Schricker, R. L., Eigelsbach, H. T., Mitten, J. Q., Hall, W. C.: Pathogenesis of tularemia in monkeys aerogenically exposed toFrancisella tularensis 425. Infection and Immunity 1972, 5: 734–744.Google Scholar
  13. 13.
    Dahlstrand, S., Ringertz, O., Zetterberg, B.: Airborne tularemia in Sweden. Scandinavian Journal of Infectious Diseases 1971, 3: 7–16.Google Scholar
  14. 14.
    Eigelsbach, H. T., Tulis, J. J., McGavran, M. H., White, J. D.: Live tularemia vaccine. I. Host-parasite relationship in monkeys vaccinated intracutaneously or aerogenically. Journal of Bacteriology 1962, 84: 1020–1027.Google Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1989

Authors and Affiliations

  • A. Tärnvik
    • 1
  • C. Henning
    • 2
  • E. Falsen
    • 3
  • G. Sandström
    • 4
  1. 1.Department of Infectious DiseasesUniversity of UmeåUmeåSweden
  2. 2.Department of Clinical BacteriologyCentral Hospital of SundsvallSundsvallSweden
  3. 3.Department of Clinical Bacteriology, Culture CollectionUniversity of GöteborgGöteborgSweden
  4. 4.Department of Cell- and MicrobiologySwedish Defense Research EstablishmentUmeåSweden

Personalised recommendations