European Journal of Pediatrics

, Volume 150, Issue 3, pp 205–208

Maternal vegan diet causing a serious infantile neurological disorder due to vitamin B12 deficiency

  • T. Kühne
  • R. Bubl
  • R. Baumgartner

DOI: 10.1007/BF01963568

Cite this article as:
Kühne, T., Bubl, R. & Baumgartner, R. Eur J Pediatr (1991) 150: 205. doi:10.1007/BF01963568


We present a 9-month-old exclusively breastfed baby of a strict vegetarian mother who had excluded all animal proteins from her diet. The patient's symptoms included dystrophy, weakness, muscular atrophy, loss of tendon reflexes, psychomotor regression and haematological abnormalities. Biochemical investigations revealed severe methylmalonic aciduria and homocystinuria in the patient, slight methylmalonic aciduria in the mother and low concentrations of serum vitamin B12 in both patient and mother.

Key words

Vitamin B12 Methylmalonic acid Homocysteine Vegetarian diet 



lactic dehydrogenase


methylmalonic acid

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • T. Kühne
    • 1
  • R. Bubl
    • 1
  • R. Baumgartner
    • 1
  1. 1.University Children's Hospital BaselBaselSwitzerland

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