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Pharmaceutisch Weekblad

, Volume 5, Issue 3, pp 109–113 | Cite as

Analysis of creams

V. Application of thin layer chromatography. Part I
  • F. J. Van De Vaart
  • A. Hulshoff
  • A. W. M. Indemans
Original Articles

Abstract

A standard procedure, consisting of twotlc systems, for the qualitative control of creams is presented. All common cream excipients, except those of very high polarity, are separated in a simple gradient elution system, using diethyl ether as the eluent in a chromatographic chamber saturated withn-pentane. The very polar cream base components are separated usingn-butanol-glacial acetic acid-water (20+2+5) as the eluent. The chromatographic behaviour of common cream excipients as well as threefna cream bases and four commercial cream bases is discussed.

Keywords

Acetic Ether Internal Medicine Standard Procedure Diethyl 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1983

Authors and Affiliations

  • F. J. Van De Vaart
    • 1
  • A. Hulshoff
    • 2
  • A. W. M. Indemans
    • 1
    • 2
  1. 1.Laboratory of the Dutch PharmacistsJL The HagueThe Netherlands
  2. 2.Pharmaceutical Laboratory, Department of Analytical PharmacyUniversity of UtrechtGH UtrechtThe Netherlands

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