Pharmaceutisch Weekblad

, Volume 7, Issue 6, pp 277–279 | Cite as

The essential oil of Apium graveolens var. secalinum and its cercaricidal activity

  • M. M. Saleh
  • J. H. Zwaving
  • Th. M. Malingré
  • R. Bos
Short Communications


The composition of the essential oil of the fresh aerial parts ofApium graveolens var.secalinum at its flowering stage, obtained from three different locations in Egypt, was investigated. The identification of the components of this oil was carried out by means of analytical GC and GC-MS. The main components in the oil are: α- and Β-pinene, myrcene, limonene,cis-Β-ocimene, γ-terpinene,cis-allo-ocimene,trans-farnesene, humulene, apiol, Β-selinene, senkyunolide and neocnidilide. Data concerning the relative concentrations of the main components of the different celery oil samples are given. The cercaricidal effect of the essential oil has been examined on cercariae, being one of the stages in the life cycles ofSchistosoma mansoni, which causes schistosomiasis. The essential oil showed in addition to a cercaricidal effect also a chemotactic effect.


Life Cycle Relative Concentration Aerial Part Limonene Schistosomiasis 
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Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1985

Authors and Affiliations

  • M. M. Saleh
    • 1
  • J. H. Zwaving
    • 2
  • Th. M. Malingré
    • 2
  • R. Bos
    • 2
  1. 1.Medicinal and Aromatic Plants Research GroupNational Research CentreDokki, CairoEgypt
  2. 2.Laboratory of PharmacognosyState University of GroningenAW GroningenThe Netherlands

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