Experientia

, Volume 45, Issue 4, pp 332–334 | Cite as

Prothymosin alpha is not a nuclear polypeptide

  • O. E. Tsitsiloni
  • P. P. Yialouris
  • K. Sekeri-Pataryas
  • A. A. Haritos
Article

Summary

Using a radioimmunoassay for the NH2-terminus of prothymosin alpha, the crossreactive material was measured in subcellular fractions of calf thymus and liver. No significant amount of crossreactive material was found in the nucleus. This provides experimental evidence against a recent hypothesis, based on structural evidence, that prothymosin alpha is a nuclear polypeptide.

Key words

Prothymosin alpha thymosin alpha 1 

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Copyright information

© Birkhäuser Verlag Basel 1989

Authors and Affiliations

  • O. E. Tsitsiloni
    • 1
  • P. P. Yialouris
    • 1
  • K. Sekeri-Pataryas
    • 2
  • A. A. Haritos
    • 1
  1. 1.Zoological Laboratory, Faculty of SciencesUniversity of AthensAthens(Greece)
  2. 2.Department of BiologyNational Research Center of Natural Sciences ‘Demokritos’Athens(Greece)

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