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Isometric relaxation in rat myocardium: Load dependence and influence of caffeine

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Summary

When caffeine plus calcium is added to the perfusing medium, isometric relaxation of rat myocardium is no longer affected by length changes occurring during the twitch. The dependence of isometric relaxation on the initial muscle length is still present and more pronounced after caffeine addition.

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References

  1. D.L. Brutsaert, N.M. De Clerck, M.A. Goethals and P.R. Housmans, J. Physiol.283, 469 (1978).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. A.J. Brady, Fedn Proc.24, 1410 (1965).

    CAS  Google Scholar 

  3. R.L. Kaufmann, R.M. Bayer and C. Harnasch, Pflügers Arch.332, 96 (1972).

    Article  CAS  PubMed  Google Scholar 

  4. B.R. Jewell and D.R. Wilkie, J. Physiol.152, 30 (1960).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. A.S. Bahler, Am. J. Physiol.220, 1983 (1971).

    Article  CAS  PubMed  Google Scholar 

  6. B. Johansson and P. Hellstrand, Acta physiol. scand.93, 167 (1975).

    Article  CAS  PubMed  Google Scholar 

  7. L. Blayney, H. Thomas, J. Muir and A. Henderson, Circulation Res.43, 520 (1978).

    Article  CAS  PubMed  Google Scholar 

  8. J.R. Blinks, C.B. Olson, B.R. Jewell and P. Braveny, Circulation Res.30, 367 (1972).

    Article  CAS  PubMed  Google Scholar 

  9. C.L. Gibbs, Physiol. Rev.58, 174 (1978).

    Article  CAS  PubMed  Google Scholar 

  10. F.J. Julian and M.R. Sollins, Circulation Res.37, 299 (1975).

    Article  CAS  PubMed  Google Scholar 

  11. R. Bodem and E.H. Sonnenblick, Am. J. Physiol.228, 250 (1975).

    Article  CAS  PubMed  Google Scholar 

  12. W.W. Parmley and E.H. Sonnenblick, Am. J. Physiol.216, 1084 (1969).

    Article  CAS  PubMed  Google Scholar 

  13. D.K. Hill, J. Physiol.221, 161 (1972).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Poggesi, C., Ricciardi, L., Reggiani, C. et al. Isometric relaxation in rat myocardium: Load dependence and influence of caffeine. Experientia 35, 1615–1617 (1979). https://doi.org/10.1007/BF01953225

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  • DOI: https://doi.org/10.1007/BF01953225

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